Journal of heterocyclic chemistry

Antineoplastic anthraquinones. II. Design and synthesis of 1, 2??Heteroannelated anthraquinones

P Chang, CF Chen

文献索引：Chang, Pong; Chen, Chia-Fu Journal of Heterocyclic Chemistry, 1996 , vol. 33, # 2 p. 367 - 371

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被引用次数: 5

摘要

Abstract Based on the “2-phenyinaphthalene-type” structural pattern hypothesis, a number of heterocycle-fused anthraquinones were designed by taking morindaparvin-A (2a) as the lead structure. The compounds we synthesized and tested for antineoplastic activity include 1, 2-alkylenedioxyanthraquinone, naphtho [2, 3-f]-quinoxaline-7, 12-dione, anthra [1, 2-d] imidazole-6, 11-dione and naphtho [2, 3-f] quinoxaline-7, 12-dione derivatives. Most of the ...