Tetrahedron Letters

Total synthesis of argyrins A and E

W Wu, Z Li, G Zhou, S Jiang

文献索引：Wu, Wenbin; Li, Zheng; Zhou, Guangbiao; Jiang, Sheng Tetrahedron Letters, 2011 , vol. 52, # 19 p. 2488 - 2491

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被引用次数: 15

摘要

The total synthesis of argyrins A and E were accomplished using a convergent strategy by condensation of one tripeptide and two dipeptide fragments. The synthesis strategy, which was developed for the protection of peptide fragments and identification of the optimum macrocylization site, can be applied to further synthetic studies involving other members of the argyrin family.