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Tetrahedron

Synthesis of the dibenzo [f, h] phthalazine and dibenzo [f, h] cinnoline skeleton via a 'Suzuki–Pd-catalyzed intramolecular arylation'and a 'Suzuki–Pschorr'approach

…, Z Riedl, G Hajós, B Van den Driessche, RA Dommisse…

文献索引:Tapolcsanyi, Pal; Maes, Bert U. W.; Monsieurs, Katrien; Lemiere, Guy L. F.; Riedl, Zsuzsanna; Hajos, Gyoergy; Van Den Driessche, Bart; Dommisse, Roger A.; Matyus, Peter Tetrahedron, 2003 , vol. 59, # 31 p. 5919 - 5926

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被引用次数: 26

摘要

Palladium-catalyzed intramolecular arylation of 2-benzyl-5-(2-bromophenyl)-4- phenylpyridazin-3 (2H)-one yielded hitherto unknown 2-benzyldibenzo [f, h] phthalazin-1 (2H)-one. The synthesis of this new tetracyclic pyridazinone from 2-benzyl-5-(2- aminophenyl)-4-phenylpyridazin-3 (2H)-one via a Pschorr type reaction was also investigated. Similarly, the construction of 2-methyldibenzo [f, h] cinnolin-3 (2H)-one from ...