Phenothiazine derivatives: mono-oxygenated compounds

DF Houston, EB Kester, F DeEds

文献索引：Houston Journal of the American Chemical Society, 1949 , vol. 71, p. 395

被引用次数: 24

摘要

Phenothiazine (I) has been shown2 to have in vitm tuberculostatic action which is somewhat diminished in the presence of serum. The oxidized derivatives known as phenothiazone (11) and thionol (111) also showed a moderate inhibiting effect, and it was postulated that their lesser effectiveness might be connected with their decreased solubility in lipids. Compounds having