Tetrahedron Letters

A solvent-free synthesis of ethyl 3, 5-diaryl-1H-pyrrole-2-carboxylates via triethylphosphite mediated reductive cyclization of ethyl 2-nitro-5-oxo-3, 5-diarylpentanoates …

R Khajuria, Y Saini, KK Kapoor

文献索引：Khajuria, Rajni; Saini, Yeshwinder; Kapoor, Kamal K. Tetrahedron Letters, 2013 , vol. 54, # 42 p. 5699 - 5702

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被引用次数: 12

摘要

Abstract Ethyl 3, 5-diaryl-1H-pyrrole-2-carboxylates have been synthesized in good yields from ethyl 2-nitro-5-oxo-3, 5-diarylpentanoates by treatment with triethylphosphite under microwave irradiation. The integrity of the mechanism proposed has been augmented by 31 P NMR and EIMS experiments.