Journal of medicinal chemistry

Experimental antileukemic agents. Preparation and structure-activity study of S-tritylcysteine and related compounds

KY Zee-Cheng, CC Cheng

文献索引：Zee-Cheng,K.-Y.; Cheng,C.C. Journal of Medicinal Chemistry, 1970 , vol. 13, p. 414 - 418

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被引用次数: 29

摘要

NHCOCH,;?; XI XXII Chemistry.-Among the lmon-n met'hods for the preparation of S- substituted cysteines7~ 20, 23-26 and S-t'ritylation reacti~ ns,~'-~~ condensation of cysteine with the appropriate aryl-substituted carbinols with BF,,* rz0 which involves initial carbonium ion formation of the carbinol followed by nucleophilic attack of the S atom of cysteine or related compounds, was adapted for the present preparation. The carbinols and ...