Bis (2-chloroalkyl) amides of Acylated Amino Acids. Modified Nitrogen Mustards1

I Levi, H Blondal, JWR Weed, AC Frosst…

文献索引：Levi,I. et al. Journal of Medicinal Chemistry, 1965 , vol. 8, p. 715 - 718

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被引用次数: 4

摘要

tion R mentioned above was concentrated at room temperature until D brown sirup was obtained. It was dissolved in 5 ml. of 0.1 S KaOH, warmed with a little Darco G-60, and filtered. Aridification of the filtrate caused the separation of a brownish oil. The aqueous phase was decanted and the oil, after washing with water and triturating with 10 ml. of methanol, slowly crystallized. The crystalline material was collected and washed with ethyl ...