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The Journal of Organic Chemistry

Synthesis of 7-fluorobenz [a] anthracene

MS Newman, KC Lilje

文献索引:Newman,M.S.; Lilje,K.C. Journal of Organic Chemistry, 1979 , vol. 44, # 8 p. 1347 - 1348

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被引用次数: 12

摘要

proved procedure which affords 5 in 55% yield from benz [a]-anthracene (6). The starting 6 was prepared by condensation of phthalaldehydic acid with naphthalene to yield 3-(1- naphthy1) phthalidell which was reduced to 2-(l-naphthylmethy1) benzoic acid12 followed by ring closure, reduction of benzanthrone, and dehydration to yield 6 in 76% overall yield. Compound 1 is being tested for carcinogenic activity.