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Micromide and guamamide: cytotoxic alkaloids from a species of the marine cyanobacterium Symploca

PG Williams, WY Yoshida, RE Moore…

文献索引:Williams, Philip G.; Yoshida, Wesley Y.; Moore, Richard E.; Paul, Valerie J. Journal of Natural Products, 2004 , vol. 67, # 1 p. 49 - 53

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被引用次数: 37

摘要

Two new cytotoxins have been isolated from a species of marine cyanobacterium belonging to the genus Symploca that was collected in Guam. These new compounds, micromide (1) and guamamide (2), were accompanied by the known lipopeptides apramides A (3), B (4), and G (5). The planar structures of both alkaloids were elucidated by standard 2D NMR techniques, and the configurations of the amino acid-derived units in 1 were determined ...