Abstract Natural and synthetic compounds characterized by an anthraquinone nucleus represent an important class of anti-neoplastic agents, the mechanism of action of which is related to intercalation into DNA. Ametantrone (AM) is a synthetic 9, 10-anthracenedione bearing two (hydroxyethylamino) ethylamino residues at positions 1 and 4; along with other anthraquinones and anthracyclines, it shares a polycyclic intercalating moiety and ...
![Naphtho[2,3-f]quinoxaline-7,12-dione, 1,2,3, 4-tetrahydro-4-(2-hydroxyethyl)-6-[[2-[(2-hydroxyethyl)amino]ethyl ]amino]-结构式](https://image.chemsrc.com/caspic/496/65271-81-0.png)
![1,4-Bis{[2-(2-hydroxyethoxy)ethyl]amino}anthra-9,10-quinone结构式](https://image.chemsrc.com/caspic/327/47645-63-6.png)