Antimalarial properties of a variety of substituted p??sulfamoylphenylazo compounds

…, SK Gupta, MH Herbert, D Chitharanjan

文献索引：Harmon; Geller; Gupta; Herbert; Chitharanjan Journal of pharmaceutical sciences, 1970 , vol. 59, # 7 p. 1031 - 1033

全文：HTML全文

被引用次数: 1

摘要

Abstract A wide variety of substituted p-sulfamoylphenylazo compounds were prepared, and their activity against Plasmodium berghei in mice was studied. A study of the effects of substitution in the sulfamoyl group revealed that substitution by pyrimidine, methylpyrimidine, and hexylresorcinol greatly increased the antimalarial activity, while substitution by thiazole, methylthiazole, and 2-methyl-3, 4-thiadiazole did not lead to a ...