Synthesis and conformational analysis of 2-amino-1, 2, 3, 4-tetrahydro-1-naphthalenols

…, D Mauleon, C Minguillon, JR Subirats…

文献索引：Delgado; Garcia; Mauleon; Minguillon; Subirats; Feliz; Lopez; Velasco Canadian Journal of Chemistry, 1988 , vol. 66, # 3 p. 517-527

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被引用次数: 11

摘要

Synthesis and conformational analysis of several cis-and (or) trans-2-amino-1, 2, 3, 4- tetrahydro-1-naphthalenols are described. Introduction of the nitrogen atom at the C (2) position of the starting tetralones 3 has been carried out through nitrosation followed by reduction of the intermediate hydroxyimino tetralone and (or) Neber rearrangement of the tosyloxy derivatives 7 ae. Stereoselective reduction of the C (1) carbonyl group of ...