Regioselective Synthesis of 2, 2-Dimethylcyclopentanone Using 2-Pyrrolidone Magnesium Salt as Electrogenerated Base.

…, M Bordeau, C Biran, J Dunoguès

文献索引：Bonafoux, Dominique; Bordeau, Michel; Biran, Claude; Dunogues, Jacques Synthetic Communications, 1998 , vol. 28, # 1 p. 93 - 98

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被引用次数: 10

摘要

Laboratoire de Chimie Organique et Organometallique associe au CNRS, Universite Bordeaux I, F-33405 Talence, France ... Abstract: An efficient, direct and regioselective preparation of 2,2- dimethylcyclopentanone, via its enolate precursor regioselectively obtained using the 2-pynolidone magnesium salt, a base electrogenerated in DME/HMPA, is reported. ... Although a-alkylation of ketones via their metal enolates (M = Li, K, ...) is of