Abstract Twenty-five 2, 2'-disubstituted N-phenylbenzenesulfonamides (2-XC 6 H 4 SO 2 NHC 6 H 4-Y-2') were synthesised and their purity checked by elemental analysis. This set of model substrates involved all possible combinations of methoxy, methyl, hydrogen, chloro, and nitro substituents. The dissociation constants of the sulfonamides were determined by potentiometric titration in methanol, pyridine, dimethyl sulfoxide, N, N- ...
