//NR (HI synthesis of heterocyclic rings, the use of the thio ethers CHaS-C\ NHR (HI has been very limited. Wheeler and Johnson6 and their students have employed methyl isothiourea in the synthesis of pyrimidines, and in one instance a substituted quinazoline,'but only in this latter case did ring closure involve loss of the CH3S-grouping. A thiourea of the type RN= C-(SCH3) NHR contains two points of attack;(a) the SCH r group ...
[Reddy, Ch. K.; Reddy, P. S. N.; Ratnam, C. V. Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, 1987 , vol. 26, # 1-12 p. 882 - 883]