Synthetic anticonvulsants, antihypoxics, and liver monooxygenase system inducers based on amides and urea. XI. Synthesis of alkyl-and arylalkylureas and their …
SS Bakibaev, RR Akhmedzhanov, VD Filimonov…
文献索引：Bakibaev, S. S.; Akhmedzhanov, R. R.; Filimonov, V. D.; Novocheeva, T. P.; Saratikov, A. S.; et al. Pharmaceutical Chemistry Journal, 1993 , vol. 27, # 9 p. 631 - 634 Khimiko-Farmatsevticheskii Zhurnal, 1993 , vol. 27, # 9 p. 27 - 29
During studies on the search for and synthesis of new compounds able to induce the liver cytochrome--P-450-dependent monooxygenase system, we have produced a series of urea derivatives (I-XVIII) and we have evaluated their enzyme-inducing activities using the hexobarbital sleep test. Alkyl-and arylalkylureas I-XVIII were prepared by combining the corresponding alkyl-and arylalkylamines with nitrourea in aqueous solution as described ...
