Substituent Effect on Acidity of Substituted 2-(4-Nitrobenzoylamino) alkanamides in Methanol-Dimethyl Sulfoxide Mixtures

P Mitaš, M Sedlák, J Kaválek

文献索引：Mitas, Petr; Sedlak, Milos; Kavalek, Jaromir Collection of Czechoslovak Chemical Communications, 1998 , vol. 63, # 1 p. 85 - 93

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被引用次数: 6

摘要

Abstract The dissociation constants of substituted 2-(4-nitrobenzoylamino) alkanamides, N- [2-(4-nitrobenzoylamino) alkanoyl] pyrrolidines, and N-alkyl-4-nitrobenzamides have been measured spectrophotometrically in 60 and 80% v/v DMSO. The pK A values of these N- acids are discussed from the point of view of substituents at the acetamide α-carbon atom.