Silphos [PCl3− n (SiO2) n]: A Heterogeneous Phosphine Reagent for the Regioselective Synthesis of vic-Haloalcohols
N Iranpoor, H Firouzabadi…
文献索引：Iranpoor, Nasser; Firouzabadi, Habib; Jamalian, Arezu Phosphorus, Sulfur and Silicon and the Related Elements, 2006 , vol. 181, # 11 p. 2615 - 2621
Silphos as a silica-based phosphine [PCl3− n (SiO2) n] provides a practical method for the conversion of epoxides to vic-haloalcohols in the presence of molecular bromine, iodine, or N-halosuccinimides (NXS, X= Cl, Br, I) in CH3CN or under solvent-free conditions at rt The simple filtration of heterogeneous Silphos oxide from the reaction mixture affords the pure vic-haloalcohols with excellent yields.
