A highly selective methodology for the direct conversion of acetals to esters

…, S Bhat, S Chandrasekaran

文献索引：Chidambaram, N.; Bhat, Shridhar; Chandrasekaran, S. Journal of Organic Chemistry, 1992 , vol. 57, # 18 p. 5013 - 5015

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被引用次数: 32

摘要

The pyrazole diester (0.5 g, 1.9 mmol) was refluxed for 10 h in 1 mL of ethanol containing 1.84 g of a 15% potassium hydroxide solution. The cold solution was diluted with water (2 mL) and acidified to pH 3.5 with 2 M HC1. The precipitate was filtered and washed with cold water and diethyl ether. Crystallization from water/ethanol yielded pure 19 (0.32 g, 81%): mp 225 OC; UV 222 (4.0); IR (KBr) 3260, 3100, 2980, 2940, 1710, 1580, 1520, 2.66-2.62 (m, ...