前往化源商城

Synthesis of 5??Substituted 1H??Tetrazoles from Nitriles and Hydrazoic Acid by Using a Safe and Scalable High??Temperature Microreactor Approach

B Gutmann, JP Roduit, D Roberge…

文献索引:Gutmann, Bernhard; Roduit, Jean-Paul; Kappe, C. Oliver; Roberge, Dominique Angewandte Chemie - International Edition, 2010 , vol. 49, # 39 p. 7101 - 7105

全文:HTML全文

被引用次数: 113

摘要

Interest in tetrazole chemistry over the past few years has been increasing rapidly, mainly as a result of the role played by this heterocyclic functionality in medicinal chemistry as a metabolically stable surrogate for carboxylic acid functionalities.[1] Additional important applications for tetrazoles are found in coordination chemistry, materials science, and as intermediates in a variety of synthetic transformations.[2] The most common synthetic ...