Green Catalysts: Solid??Phase Peptide Carbene Ligands in Aqueous Transition??Metal Catalysis

K Worm??Leonhard, M Meldal

文献索引：Worm-Leonhard, Kasper; Meldal, Morten European Journal of Organic Chemistry, 2008 , # 31 p. 5244 - 5253

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被引用次数: 23

摘要

Abstract A series of functionalized imidazolium ions containing a pyridine moiety and carboxylic acid functionality has been synthesized in solution. These compounds serve as N- heterocyclic carbene precursors and were attached to a dipeptide on solid support by means of standard peptide coupling techniques. Treatment with base generated the corresponding carbenes, which were directly complexed to palladium (II) and ...