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Microwave enhanced reduction of nitro and azido arenes to N-arylformamides employing Zn–HCOONH 4: synthesis of 4 (3H)-quinazolinones and pyrrolo [2, 1-c][1, 4] …

…, KS Reddy, BR Prasad, AH Babu, AV Ramana

文献索引:Kamal, Ahmed; Srinivasa Reddy; Rajendra Prasad; Hari Babu; Ramana, A. Venkata Tetrahedron Letters, 2004 , vol. 45, # 34 p. 6517 - 6521

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被引用次数: 59

摘要

Microwave mediated reduction of nitro and azido arenes to N-arylformamides using Zn– HCOONH4 is described. In the absence of microwave conditions, this methodology affords amines. This protocol has been extended to the synthesis of pyrrolo [2, 1-c][1, 4] benzodiazepines and 4 (3H)-quinazolinones.