Antibiotic-resistant strains of pathogenic bacteria are increasingly prevalent in hospitals and the community. Novel agents that target mechanisms different from those of currently approved antibiotics are urgently needed to combat these bacterial pathogens to ensure future therapeutic success. [ 1 1. Payne , DJ Microbiology: Desperately seeking new antibiotics . Science 2008 , 321 , 1644 – 1645 . [CrossRef], [Web of Science ®] View all references ] Recent studies ...