An Efficient and Practical Synthesis of Aryl and Hetaryl α-Keto Esters

A Raghunadh, SB Meruva, NA Kumar, GS Kumar…

文献索引：Raghunadh, Akula; Meruva, Suresh Babu; Kumar, Nuka Anil; Kumar, Gudla Santosh; Rao, L. Vaikunta; Syamkumar Synthesis, 2012 , vol. 2012, # 2 p. 283 - 289

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被引用次数: 12

摘要

Abstract A general and highly efficient method was developed for the synthesis of α-keto esters by oxidative esterification of 2, 2-dibromo-1-(het) arylethanones by sequential treatment with dimethyl sulfoxide and an alkanol. The versatility of the reaction was established by synthesizing a range of α-keto esters by treatment of 2, 2-dibromoethanones, derived from aryl or hetaryl ketones, with dimethyl sulfoxide and a cyclic or acyclic primary ...