Trityl chloride as a novel and efficient organic catalyst for room temperature preparation of bis (indolyl) methanes under solvent-free conditions in neutral media

A Khalafi-Nezhad, A Parhami, A Zare, ARM Zare…

文献索引：Khalafi-Nezhad; Parhami; Zare; Moosavi Zare; Hasaninejad; Panahi Synthesis, 2008 , # 4 p. 617 - 621

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被引用次数: 57

摘要

Abstract A simple, clean, and highly efficient solvent-free procedure for the preparation of bis (1H-indol-3-yl) methanes is described from the reaction of carbonyl compounds (aldehydes and ketones) with 1H-indole in the presence of trityl chloride as a catalyst. The reaction proceeds rapidly in high yields at room temperature in a neutral medium. A proposed mechanism is suggested based upon former reactions and calculated results.