Notes-Fluoro Analogs of Prostigmine

S Shapiro, T Bazga, L Freedman

文献索引：Shapiro,S.L. et al. Journal of Organic Chemistry, 1960 , vol. 25, p. 2064 - 2066

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被引用次数: 5

摘要

In particular, employment of a strongly meta orienting trifluoromethyl group2 evaluated replacement of the electronically similar trimethylammonium groupap4 of I. The steric effects of the trifluoromethyl group5 arid its incorporation into biologically active agents6 have been recently described. The meta relationship of the oxy function in I1 was indicated on pharmacological7 and chemica12+ 12 bases.