Discovery of an orally efficacious inhibitor of coagulation factor Xa which incorporates a neutral P1 ligand

YM Choi-Sledeski, R Kearney, G Poli…

文献索引：Journal of Medicinal Chemistry, , vol. 46, # 5 p. 681 - 684

被引用次数: 77

摘要

... Journal of Medicinal ... Department of Medicinal Chemistry and Department of Biology, Aventis Pharmaceuticals, Route 202-206, Bridgewater, New Jersey ... 681–684. DOI: 10.1021/jm020384z. Publication Date (Web): February 4, 2003. Copyright © 2003 American Chemical Society. ...

Discovery of an orally efficacious inhibitor of coagulation ...

[Choi-Sledeski, Yong Mi; Kearney, Robert; Poli, Gregory; Pauls, Henry; Gardner, Charles; Gong, Yong; Becker, Michael; Davis, Roderick; Spada, Alfred; Liang, Guyan; Chu, Valeria; Brown, Karen; Collussi, Dennis; Leadley Jr., Robert; Rebello, Sam; Moxey, Phillip; Morgan, Suzanne; Bentley, Ross; Kasiewski, Charles; Maignan, Sebastien; Guilloteau, Jean-Pierre; Mikol, Vincent Journal of Medicinal Chemistry, 2003 , vol. 46, # 5 p. 681 - 684]

Synthesis of 2-quinolones via palladium-catalyzed carbonylat...

[Journal of Organic Chemistry, , vol. 69, # 20 p. 6772 - 6780]