Chemistry & Biodiversity 2006-01-01

Structure elucidation and antibacterial activity of new fungal metabolites of sclareol.

M Iqbal Choudhary, Zafar Ali Siddiqui, Samreen Hussain

文献索引：Chem. Biodivers. 3(1) , 54-61, (2006)

摘要

The transformation of the antibacterial diterpene sclareol (1) by two different fungal strains was investigated (Scheme). In the presence of Rhizopus stolonifer, (3beta)-3-hydroxysclareol (2), 18-hydroxysclareol (3), (6alpha)-6,18-dihydroxysclareol (4), and (11S)-11,18-dihydroxysclareol (5) were formed. Fermentation of 1 with Fusarium lini afforded (1beta)-1-hydroxysclareol (6) and (12S)-12-hydroxysclareol (7). Compounds 4-7 were identified as new compounds, and some of them were active against Bacillus subtilis (Table 3).

结构式	名称/CAS号	分子式	全部文献
	香紫苏醇 CAS:515-03-7	C₂₀H₃₆O₂

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摘要

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