Nature Reviews: Drug Discovery 2008-12-01

End of the line for cannabinoid receptor 1 as an anti-obesity target?

Dan Jones

文献索引：Nat. Rev. Drug Discov. 7(12) , 961-2, (2008)

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摘要

A wave of terminations of development programmes for cannabinoid receptor 1 blockers for obesity indicates the demise of a drug class that was once anticipated to yield blockbusters. Nevertheless, lessons learned might help salvage something for future such approaches.