Impurity Profile Study of Venlafaxine Hydrochloride, an Antipsychotic Drug Substance

…, KS Kumar, PP Reddy, B Satyanarayana

文献索引：Saravanan, Mohanarangam; Kumar, Karra Suresh; Reddy, Padi Pratap; Satyanarayana, Bollikonda Synthetic Communications, 2010 , vol. 40, # 13 p. 1880 - 1886

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被引用次数: 3

摘要

Venlafaxine hydrochloride is a phenyl ethylamine derivative, used for the treatment of depression. During the process development of venlafaxine hydrochloride, six process- related potential impurities were detected in high-performance liquid chromatography. All these impurities were identified, synthesized, and subsequently characterized by their respective spectral data (IR, mass, 1H NMR, and 13C NMR) as described in this article.