Organic letters

Chemoselective Esterification and Amidation of Carboxylic Acids with Imidazole Carbamates and Ureas

ST Heller, R Sarpong

文献索引：Heller, Stephen T.; Sarpong, Richmond Organic Letters, 2010 , vol. 12, # 20 p. 4572 - 4575

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被引用次数: 40

摘要

The chemoselective esterification of carboxylic acids is a ubiquitous synthetic operation. In addition to the venerable Fischer esterification,(1) numerous other methods have been developed toward this end. Transformations that involve activation of the carboxylic acid group have become a mainstay of ester synthesis, and though substantial progress has been made in this area,(2) acid activation often adds an additional step and can be challenging in the presence of ...