The Journal of Organic Chemistry

A Modified Friedlander Condensation for the Synthesis of 3-Hydroxyquinoline-2-carboxylates

DL Boger, JH Chen

文献索引：Boger, Dale L.; Chen, J.-H. Journal of Organic Chemistry, 1995 , vol. 60, # 22 p. 7369 - 7371

全文：HTML全文

被引用次数: 31

摘要

In conjunction with efforts on the total synthesis of sandramycin, l quinaldopeptin, 2 BE22179, 3 and the luzopeptins, 4 symmetrical cyclic decadepsipeptides possessing a 2- fold axis of symmetry which exhibit highaffinity sequence-selective DNA binding with bisintercalation of the pendant heterocyclic chromophores, 5B6 we required access to suitably protected derivatives of the 3-hydroxyquinoline-2-carboxylic acids la and lb and ...