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Inhibition of 1-deoxy-D-xylulose-5-phosphate reductoisomerase by lipophilic phosphonates: SAR, QSAR, and crystallographic studies

L Deng, J Diao, P Chen, V Pujari, Y Yao…

文献索引:Journal of Medicinal Chemistry, , vol. 54, # 13 p. 4721 - 4734

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被引用次数: 45

摘要

... Journal of Medicinal ... Address: Department of Pharmacology, Baylor College of Medicine, 1 Baylor Plaza, Houston, TX 77030. ... Medicinal chemistry studies based on the structures of 1 and 2 have been carried out for the past decade.(8) Although most modifications resulted in ...