Summary The rate of the vapor phase bromination of pyridine at 500'to form 2- bromopyridine is found to be substantially increased by preheating the vapors of the reactants. Various methods for the preparation of 3-bromopyridine have been studied and evaluated and a procedure by which this compound may be prepared in relatively large quantities and in 35-40% yields by the pyrolysis of pyridine hydrochloride perbromide has ...
