Synthesis of substituted pyridinones from the combination of Fe2 (. mu.-CH2)(CO) 8 with phosphinimines and alkynes

…, TE Snead, GL Geoffroy, AL Rheingold

文献索引：Mirkin, Chad A.; Lu, Kuang-Lieh; Snead, Thomas E.; Geoffroy, Gregory L.; Rheingold, Arnold L. Journal of the American Chemical Society, 1990 , vol. 112, # 7 p. 2809 - 2810

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被引用次数: 11

摘要

The pyridinone ring is an integral unit of many important molecules. 2-Pyridinones in particular have therapeutic value1a, 2 and are versatile synthetic intermediates for many alkaloids. 2 A continuing need exists for improved synthetic routes to pyridinones that tolerate a wide variety of substituents with a high degree of regiospecificity in ring substitution. Previous organometallic routes to 2-pyridinones have generally involved ...