Design and synthesis of 3, 7-diarylimidazopyridines as inhibitors of the VEGF-receptor KDR

Z Wu, ME Fraley, MT Bilodeau, ML Kaufman…

文献索引：Bioorganic and Medicinal Chemistry Letters, , vol. 14, # 4 p. 909 - 912

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被引用次数: 42

摘要

... Bioorganic & Medicinal Chemistry Letters. ... Departments of Medicinal Chemistry and Cancer ... First, we simply extended the chemistry illustrated in Scheme 1 to replace the 3-phenyl with different aryl groups via palladium catalyzed cross-coupling reactions of compound 9. The ...