Tetrahedron

Tandem synthesis of substituted 2, 7-naphthyridin-1 (7H)-ones via Reissert reaction/intramolecular nucleophilic addition/oxidation dehydrogenation

H Tan, J Wang, Y Zhang, Y Xing, Q Sun, R Li

文献索引：Tan, Hailiang; Wang, Jie; Zhang; Xing, Yongning; Sun, Qi; Li, Runtao Tetrahedron, 2013 , vol. 69, # 38 p. 8299 - 8304

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被引用次数: 2

摘要

Abstract A convenient method for the synthesis of substituted 2, 7-naphthyridin-1 (7H)-ones has been developed. This method was carried out starting from a simple nicotinamide salts via a tandem process including Reissert reaction, intramolecular nucleophilic addition and oxidation dehydrogenation. Using this method, a variety of substituted 2, 7-naphthyridin-1 (7H)-ones were obtained in good yields.