Cu-catalyzed esterification reaction via aerobic oxygenation and C–C bond cleavage: An approach to α-ketoesters

C Zhang, P Feng, N Jiao

文献索引：Zhang, Chun; Feng, Peng; Jiao, Ning Journal of the American Chemical Society, 2013 , vol. 135, # 40 p. 15257 - 15262

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被引用次数: 96

摘要

The Cu-catalyzed novel aerobic oxidative esterification reaction of 1, 3-diones for the synthesis of α-ketoesters has been developed. This method combines C–C σ-bond cleavage, dioxygen activation and oxidative C–H bond functionalization, as well as provides a practical, neutral, and mild synthetic approach to α-ketoesters which are important units in many biologically active compounds and useful precursors in a variety of functional group ...