Synthesis and properties of ligands based on benzo [g] quinoline

E Taffarel, S Chirayil, RP Thummel

文献索引：Taffarel, Emmanuelle; Chirayil, Sarah; Thummel, Randolph P. Journal of Organic Chemistry, 1994 , vol. 59, # 4 p. 823 - 828

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被引用次数: 30

摘要

The preparation of 3-amino-2-naphthaldehyde is described. Ammonolysis of 3-hydroxy-2- naphthoic acid affords the corresponding amino acid which can be esterified and then reduced with LAH. Protection of the amino group, MnO2 oxidation of the primary alcohol to an aldehyde, and deprotection gave the amino aldehyde which is an excellent Friedlbder synthon for benzo [glquinolines. Dimethylene-bridged analogues of 2, 2 '-bipyridine and 2, ...