Journal of organometallic chemistry

Asymmetric hydrogenation of 1-phenylethenylboronic acid and esters for the synthesis of chiral organoboron compounds

M Ueda, A Saitoh, N Miyaura

文献索引：Ueda, Masato; Saitoh, Atsushi; Miyaura, Norio Journal of Organometallic Chemistry, 2002 , vol. 642, # 1-2 p. 145 - 147

全文：HTML全文

被引用次数: 21

摘要

The hydrogenation of ethanediol 1-phenylethenylboronic ester was carried out at− 20° C under a hydrogen atmosphere (9 atm) in the presence of [Rh (cod) 2] BF4–(R)-BINAP (3 mol%). After alkaline hydrogen peroxide oxidation, the reaction gave 1-phenylethanol with 80% ee