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Synthesis and antifungal activity against strains of candida albicans of 6??fluoro??4 (5 or 7)??chloro??2??(difluorobenzoyl) aminobenzothiazoles

D Armenise, N De Laurentis, A Reho…

文献索引:Armenise, Domenico; De Laurentis, Nicolino; Reho, Antonia; Rosato, Antonio; Morlacchi, Flaviano Journal of Heterocyclic Chemistry, 2004 , vol. 41, # 5 p. 771 - 775

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被引用次数: 10

摘要

Abstract A series of 6-fluoro-4-(5 or 7)-chloro-2-(difluorobenzoyl) aminobenzothiazoles 3a-r were prepared to investigate their potential biological activity. In this work, the results of their in vitro antifungal activity against some strains of Candida albicans are reported. It was found that some derivatives displayed antifungal activity higher than that for 3k [1a] compound already described in literature.