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Tetrahedron Letters

Copper (I) 3-methylsalicylate, an efficient catalyst for N-arylation of heterocycles under moderate reaction conditions

AA Farahat, DW Boykin

文献索引:Farahat, Abdelbasset A.; Boykin, David W. Tetrahedron Letters, 2014 , vol. 55, # 19 p. 3049 - 3051

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被引用次数: 7

摘要

Abstract Copper (I) 3-methylsalicylate mediates N-arylation reactions of both aliphatic and aromatic heterocycles under moderate reaction conditions. Both electron rich and electron poor aryl bromides and a diverse set of N-heterocycles were allowed to react and gave N- arylation products in high yields which demonstrated the efficiency and utility of this catalyst.