Tetrahedron letters

Mild and efficient method for the cleavage of cyclic and acyclic ethers by iodine under solvent-free conditions

JS Yadav, BVS Reddy, PMK Reddy, MK Gupta

文献索引：Yadav; Reddy; Reddy, P. Murali Krishna; Gupta, Manoj K. Tetrahedron Letters, 2005 , vol. 46, # 49 p. 8493 - 8495

全文：HTML全文

被引用次数: 25

摘要

Ethers undergo smooth cleavage with acyl chlorides in the presence of a catalytic amount of elemental iodine under extremely mild conditions to give the corresponding halo esters. This new procedure offers significant advantages such as high conversions, short reaction times and enhanced selectivity together with mild reaction conditions, which makes it an attractive strategy.