The synthesis of a chiral β-amino acid derivative by the Grignard reaction of an aspartic acid equivalent

…, X Peng, X Tao, J Mao, J Wan, X Pan

文献索引：Liu, Feng; Yu, Wansheng; Ou, Wenhua; Xu, Xiaojiong; Ruan, Libo; Wang, Xiaoke; Li, Yiming; Peng, Xijiang; Tao, Xiaohu; Mao, Jun; Wan, Jiaomei; Pan, Xianhua Journal of Chemical Research, 2010 , # 9 p. 517 - 519

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被引用次数: 5

摘要

A novel synthetic route to chiral β-amino acid derivative has been developed by a Grignard reaction of 2, 4, 5-trifluorophenyl magnesium bromide with the Weinreb amide derivative of L- aspartic acid. The aspartic equivalent was synthesised from L-aspartic acid in four steps, ...