Angewandte Chemie. International edition in English 2013-04-22

Identification of cystathionine β-synthase inhibitors using a hydrogen sulfide selective probe.

Megan K Thorson, Tomas Majtan, Jan P Kraus, Amy M Barrios

文献索引：Angew. Chem. Int. Ed. Engl. 52(17) , 4641-4644, (2013)

全文：HTML全文

摘要

Buzzing with activity: A hydrogen sulfide selective fluorogenic probe, 7-azido-4-methylcoumarin (AzMC), serves as a highly sensitive assay for cystathionine β-synthase activity, and is suitable for the high-throughput discovery of novel enzyme inhibitors.Copyright © 2013 WILEY-VCH Verlag GmbH & Co. KGaA, Weinheim.