Abstract Possibilities and limitations of chemoenzymatic synthesis of novel structural analogues of an antiviral preparation of Ribavirin (1-β-D-ribofuranosyl-1, 2, 4-triazole-3- carboxamide) were established. A synthesis of various amides of 1 H-1, 2, 4-triazole-3- carboxylic acid and its 5-substituted analogues—potential substrates of purine nucleoside phosphorylase—has been described. Comparative efficiency of preparation methods of ...
