Journal of Combinatorial Chemistry 2008-01-01

Combinatorial libraries of bis-heterocyclic compounds with skeletal diversity.

Miroslav Soural, Isabelle Bouillon, Viktor Krchnák

文献索引：J. Comb. Chem. 10(6) , 923-33, (2008)

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摘要

Combinatorial solid-phase synthesis of bis-heterocyclic compounds, characterized by the presence of two heterocyclic cores connected by a spacer of variable length/structure, provided structurally heterogeneous libraries with skeletal diversity. Both heterocyclic rings were assembled on resin in a combinatorial fashion.