Journal of Organic Chemistry
2005-06-10
Synthesis of isocoumarins via Pd/C-mediated reactions of o-iodobenzoic acid with terminal alkynes.
Venkataraman Subramanian, Venkateswara Rao Batchu, Deepak Barange, Manojit Pal
文献索引：J. Org. Chem. 70(12) , 4778-83, (2005)
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摘要
The coupling reaction of o-iodobenzoic acid with terminal alkynes by using a catalyst system of 10% Pd/C-Et3N-CuI-PPh3 has been studied in a variety of solvents. 3-Substituted isocoumarins were formed in good yields and with good regioselectivity when the reaction was performed in EtOH.
相关化合物
| 结构式 | 名称/CAS号 | 分子式 | 全部文献 |
|---|---|---|---|
 |
邻碘苯甲酸
CAS:88-67-5 |
C7H5IO2 |
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