The yield of the acetylation of 3 was increased from 50% with acetic anhydride (and no yield reported with acetyl to 85% by use of excess distilled acetic anhydride and of lower temperature (-12 C); at room temperature, formation of polymeric material prevented extraction of the product. Modification of the nitration of 516.1" 20 by use of an excess of fuming nitric and conc. sulfuric acids and of lower temperature (-l2T) led to an increased ...
