Some 6-Substituted 3-Aryl-7-oxothiazolo [4, 5-d] pyrimidin-2 (3 H)-thione Derivatives and Their Antimicrobial Activities
S Demirayak, FD Ali, BS Osman…
文献索引:Demirayak, Seref; Ali, Faten Dali; Osman, Baland Sirvan; Tunali, Yagmur Phosphorus, Sulfur and Silicon and the Related Elements, 2007 , vol. 182, # 8 p. 1793 - 1803
In this study, 3-aryl-6-substituted thiazolopyrimidin-2 (3H)-thione derivatives 4 and 6 have been synthesized by reacting thiazolopyrimidines 2 with ω-bromoacetophenone 3 and 2- chloro-N-(2-thiazolyl) acetamides 5. The structure elucidation of the obtained compounds was performed by IR, 1 H-NMR, MASS spectroscopy, and elemental analyses. The antibacterial and antifungal activities of the compounds were investigated, and it was ...